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Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL

Casitas B-lineage lymphoma (CBL) is an E3 ubiquitin ligase and a molecule of adaptor that we have shown is important for non-small-cell lung cancer (NSCLC). We investigated if MET is a target of CBL and if enhanced in CBL-altered NSCLC. We showed that CBL wildtype cells have lower MET expression tha...

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Detalles Bibliográficos
Autores principales:	Tan, Yi-Hung Carol, Mirzapoiazova, Tamara, Won, Brian M., Zhu, Li, Srivastava, Minu K., Vokes, Everett E., Husain, Aliya N., Batra, Surinder K., Sharma, Sherven, Salgia, Ravi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569108/ https://www.ncbi.nlm.nih.gov/pubmed/28835699 http://dx.doi.org/10.1038/s41598-017-09078-4

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