Association of autoimmune hepatitis type 1 in a child with Evans syndrome

Autoimmune hepatitis (AIH) is a progressive liver disease that is often associated with extrahepatic autoimmune disorders. Evans syndrome (ES) is a rare autoimmune disorder, which is characterized by immune thrombocytopenia and autoimmune hemolytic anemia. Association of AIH with ES is rare, especia...

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Autores principales: Jarasvaraparn, Chaowapong, Imran, Hamayun, Siddiqui, Abdul, Wilson, Felicia, Gremse, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569276/
https://www.ncbi.nlm.nih.gov/pubmed/28878866
http://dx.doi.org/10.4254/wjh.v9.i23.1008
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author Jarasvaraparn, Chaowapong
Imran, Hamayun
Siddiqui, Abdul
Wilson, Felicia
Gremse, David A
author_facet Jarasvaraparn, Chaowapong
Imran, Hamayun
Siddiqui, Abdul
Wilson, Felicia
Gremse, David A
author_sort Jarasvaraparn, Chaowapong
collection PubMed
description Autoimmune hepatitis (AIH) is a progressive liver disease that is often associated with extrahepatic autoimmune disorders. Evans syndrome (ES) is a rare autoimmune disorder, which is characterized by immune thrombocytopenia and autoimmune hemolytic anemia. Association of AIH with ES is rare, especially in children. We report a 3-year-old female with a past medical history of ES who presented with jaundice and significant transaminitis due to AIH type 1. She required multiple treatments with steroids as well as azathioprine, intravenous immunoglobulin and a course of rituximab.
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spelling pubmed-55692762017-09-06 Association of autoimmune hepatitis type 1 in a child with Evans syndrome Jarasvaraparn, Chaowapong Imran, Hamayun Siddiqui, Abdul Wilson, Felicia Gremse, David A World J Hepatol Case Report Autoimmune hepatitis (AIH) is a progressive liver disease that is often associated with extrahepatic autoimmune disorders. Evans syndrome (ES) is a rare autoimmune disorder, which is characterized by immune thrombocytopenia and autoimmune hemolytic anemia. Association of AIH with ES is rare, especially in children. We report a 3-year-old female with a past medical history of ES who presented with jaundice and significant transaminitis due to AIH type 1. She required multiple treatments with steroids as well as azathioprine, intravenous immunoglobulin and a course of rituximab. Baishideng Publishing Group Inc 2017-08-18 2017-08-18 /pmc/articles/PMC5569276/ /pubmed/28878866 http://dx.doi.org/10.4254/wjh.v9.i23.1008 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Jarasvaraparn, Chaowapong
Imran, Hamayun
Siddiqui, Abdul
Wilson, Felicia
Gremse, David A
Association of autoimmune hepatitis type 1 in a child with Evans syndrome
title Association of autoimmune hepatitis type 1 in a child with Evans syndrome
title_full Association of autoimmune hepatitis type 1 in a child with Evans syndrome
title_fullStr Association of autoimmune hepatitis type 1 in a child with Evans syndrome
title_full_unstemmed Association of autoimmune hepatitis type 1 in a child with Evans syndrome
title_short Association of autoimmune hepatitis type 1 in a child with Evans syndrome
title_sort association of autoimmune hepatitis type 1 in a child with evans syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569276/
https://www.ncbi.nlm.nih.gov/pubmed/28878866
http://dx.doi.org/10.4254/wjh.v9.i23.1008
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