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Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of K(ATP) channels
BACKGROUND: Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in cellular functions. Accumulating lines of evidence indicate that in addition to activating PKC, PMA also produces some regulatory effects...
Autores principales: | Suga, Sechiko, Wu, Jie, Ogawa, Yoshiji, Takeo, Teruko, Kanno, Takahiro, Wakui, Makoto |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC55693/ https://www.ncbi.nlm.nih.gov/pubmed/11560763 http://dx.doi.org/10.1186/1471-2210-1-3 |
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