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Increase of cells expressing PD‐1 and PD‐L1 and enhancement of IFN‐γ production via PD‐1/PD‐L1 blockade in bovine mycoplasmosis
INTRODUCTION: Bovine mycoplasma, chiefly Mycoplasma bovis, is a pathogen that causes pneumonia, mastitis, arthritis, and otitis media in cattle. This pathogen exerts immunosuppressive effects, such as the inhibition of interferon production. However, the mechanisms involved in bovine mycoplasmosis h...
Autores principales: | Goto, Shinya, Konnai, Satoru, Okagawa, Tomohiro, Nishimori, Asami, Maekawa, Naoya, Gondaira, Satoshi, Higuchi, Hidetoshi, Koiwa, Masateru, Tajima, Motoshi, Kohara, Junko, Ogasawara, Satoshi, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569371/ https://www.ncbi.nlm.nih.gov/pubmed/28544524 http://dx.doi.org/10.1002/iid3.173 |
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