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Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study

The identification of the predictive factors and biological markers associated with treatment-related changes in the symptoms of Internet gaming disorder (IGD) may provide a better understanding of the pathophysiology underlying this condition. Thus, the present study aimed to identify neurophysiolo...

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Autores principales: Kim, Yeon Jin, Lee, Jun-Young, Oh, Sohee, Park, Minkyung, Jung, Hee Yeon, Sohn, Bo Kyung, Choi, Sam-Wook, Kim, Dai Jin, Choi, Jung-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569420/
https://www.ncbi.nlm.nih.gov/pubmed/28225502
http://dx.doi.org/10.1097/MD.0000000000006178
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author Kim, Yeon Jin
Lee, Jun-Young
Oh, Sohee
Park, Minkyung
Jung, Hee Yeon
Sohn, Bo Kyung
Choi, Sam-Wook
Kim, Dai Jin
Choi, Jung-Seok
author_facet Kim, Yeon Jin
Lee, Jun-Young
Oh, Sohee
Park, Minkyung
Jung, Hee Yeon
Sohn, Bo Kyung
Choi, Sam-Wook
Kim, Dai Jin
Choi, Jung-Seok
author_sort Kim, Yeon Jin
collection PubMed
description The identification of the predictive factors and biological markers associated with treatment-related changes in the symptoms of Internet gaming disorder (IGD) may provide a better understanding of the pathophysiology underlying this condition. Thus, the present study aimed to identify neurophysiological markers associated with symptom changes in IGD patients and to identify factors that may predict symptom improvements following outpatient treatment with pharmacotherapy. The present study included 20 IGD patients (mean age: 22.71 ± 5.47 years) and 29 healthy control subjects (mean age: 23.97 ± 4.36 years); all IGD patients completed a 6-month outpatient management program that included pharmacotherapy with selective serotonin reuptake inhibitors. Resting-state electroencephalography scans were acquired prior to and after treatment, and the primary treatment outcome was changes in scores on Young's Internet Addiction Test (IAT) from pre- to posttreatment. IGD patients showed increased resting-state electroencephalography activity in the delta and theta bands at baseline, but the increased delta band activity was normalized after 6 months of treatment and was significantly correlated with improvements in IGD symptoms. Additionally, higher absolute theta activity at baseline predicted a greater possibility of improvement in addiction symptoms following treatment, even after adjusting for the effects of depressive or anxiety symptoms. The present findings demonstrated that increased slow-wave activity represented a state neurophysiological marker in IGD patients and suggested that increased theta activity at baseline may be a favorable prognostic marker for this population.
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spelling pubmed-55694202018-06-29 Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study Kim, Yeon Jin Lee, Jun-Young Oh, Sohee Park, Minkyung Jung, Hee Yeon Sohn, Bo Kyung Choi, Sam-Wook Kim, Dai Jin Choi, Jung-Seok Medicine (Baltimore) 6500 The identification of the predictive factors and biological markers associated with treatment-related changes in the symptoms of Internet gaming disorder (IGD) may provide a better understanding of the pathophysiology underlying this condition. Thus, the present study aimed to identify neurophysiological markers associated with symptom changes in IGD patients and to identify factors that may predict symptom improvements following outpatient treatment with pharmacotherapy. The present study included 20 IGD patients (mean age: 22.71 ± 5.47 years) and 29 healthy control subjects (mean age: 23.97 ± 4.36 years); all IGD patients completed a 6-month outpatient management program that included pharmacotherapy with selective serotonin reuptake inhibitors. Resting-state electroencephalography scans were acquired prior to and after treatment, and the primary treatment outcome was changes in scores on Young's Internet Addiction Test (IAT) from pre- to posttreatment. IGD patients showed increased resting-state electroencephalography activity in the delta and theta bands at baseline, but the increased delta band activity was normalized after 6 months of treatment and was significantly correlated with improvements in IGD symptoms. Additionally, higher absolute theta activity at baseline predicted a greater possibility of improvement in addiction symptoms following treatment, even after adjusting for the effects of depressive or anxiety symptoms. The present findings demonstrated that increased slow-wave activity represented a state neurophysiological marker in IGD patients and suggested that increased theta activity at baseline may be a favorable prognostic marker for this population. Wolters Kluwer Health 2017-02-24 /pmc/articles/PMC5569420/ /pubmed/28225502 http://dx.doi.org/10.1097/MD.0000000000006178 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6500
Kim, Yeon Jin
Lee, Jun-Young
Oh, Sohee
Park, Minkyung
Jung, Hee Yeon
Sohn, Bo Kyung
Choi, Sam-Wook
Kim, Dai Jin
Choi, Jung-Seok
Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study
title Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study
title_full Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study
title_fullStr Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study
title_full_unstemmed Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study
title_short Associations between prospective symptom changes and slow-wave activity in patients with Internet gaming disorder: A resting-state EEG study
title_sort associations between prospective symptom changes and slow-wave activity in patients with internet gaming disorder: a resting-state eeg study
topic 6500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569420/
https://www.ncbi.nlm.nih.gov/pubmed/28225502
http://dx.doi.org/10.1097/MD.0000000000006178
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