Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria

OBJECTIVE(S): Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect comparable to that of IBMX (3-isobutyl-1-meth...

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Detalles Bibliográficos
Autores principales: Hosseini, Azar, Shafiee-Nick, Reza, Sadeghian, Hamid, Parsaee, Heydar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569452/
https://www.ncbi.nlm.nih.gov/pubmed/28868120
http://dx.doi.org/10.22038/IJBMS.2017.8831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569452/
https://www.ncbi.nlm.nih.gov/pubmed/28868120
http://dx.doi.org/10.22038/IJBMS.2017.8831

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