IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis

BACKGROUND: Intracellular bacterium, Mycobacterium tuberculosis (M. tb), infects specifically macrophages as host cells. IRAK-M, a member of IRAK family, is a negative regulator in TLR signaling and specifically expresses in monocytes and macrophages. The role of IRAK-M in intracellular growth of M....

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Detalles Bibliográficos
Autores principales: Shen, Pei, Li, Quan, Ma, Jilei, Tian, Maopeng, Hong, Fei, Zhai, Xinjie, Li, Jianrong, Huang, Hanju, Shi, Chunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569470/
https://www.ncbi.nlm.nih.gov/pubmed/28835201
http://dx.doi.org/10.1186/s12866-017-1095-2

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