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Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus
BACKGROUND: Human papillomavirus (HPV) has been identified as the primary etiologic factor of cervical cancer, the fourth leading cause of cancer death in females worldwide. We have previously shown that coadministration of DNA encoding L1 capsid protein of Bovine papillomavirus (BPV) can enhance th...
Autores principales: | Yang, Andrew, Peng, Shiwen, Farmer, Emily, Zeng, Qi, Cheng, Max A., Pang, Xiaowu, Wu, T. -C., Hung, Chien-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569540/ https://www.ncbi.nlm.nih.gov/pubmed/28852471 http://dx.doi.org/10.1186/s13578-017-0171-5 |
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