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Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD

OBJECTIVE: To assess and compare the prevalence of comorbidities and risk factors for cardiovascular disease (CVD) in COPD patients according to disease severity. METHODS: The study included 25 patients with mild-to-moderate COPD (68% male; mean age, 65 ± 8 years; mean FEV(1), 73 ± 15% of predicted)...

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Autores principales: Caram, Laura Miranda de Oliveira, Ferrari, Renata, Naves, Cristiane Roberta, Coelho, Liana Sousa, do Vale, Simone Alves, Tanni, Suzana Erico, Godoy, Irma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569610/
https://www.ncbi.nlm.nih.gov/pubmed/27383930
http://dx.doi.org/10.1590/S1806-37562015000000121
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author Caram, Laura Miranda de Oliveira
Ferrari, Renata
Naves, Cristiane Roberta
Coelho, Liana Sousa
do Vale, Simone Alves
Tanni, Suzana Erico
Godoy, Irma
author_facet Caram, Laura Miranda de Oliveira
Ferrari, Renata
Naves, Cristiane Roberta
Coelho, Liana Sousa
do Vale, Simone Alves
Tanni, Suzana Erico
Godoy, Irma
author_sort Caram, Laura Miranda de Oliveira
collection PubMed
description OBJECTIVE: To assess and compare the prevalence of comorbidities and risk factors for cardiovascular disease (CVD) in COPD patients according to disease severity. METHODS: The study included 25 patients with mild-to-moderate COPD (68% male; mean age, 65 ± 8 years; mean FEV(1), 73 ± 15% of predicted) and 25 with severe-to-very severe COPD (males, 56%; mean age, 69 ± 9 years; mean FEV(1), 40 ± 18% of predicted). Comorbidities were recorded on the basis of data obtained from medical charts and clinical evaluations. Comorbidities were registered on the basis of data obtained from medical charts and clinical evaluations. The Charlson comorbidity index was calculated, and the Hospital Anxiety and Depression Scale (HADS) score was determined. RESULTS: Of the 50 patients evaluated, 38 (76%) had been diagnosed with at least one comorbidity, 21 (42%) having been diagnosed with at least one CVD. Twenty-four patients (48%) had more than one CVD. Eighteen (36%) of the patients were current smokers, 10 (20%) had depression, 7 (14%) had dyslipidemia, and 7 (14%) had diabetes mellitus. Current smoking, depression, and dyslipidemia were more prevalent among the patients with mild-to-moderate COPD than among those with severe-to-very severe COPD (p < 0.001, p = 0.008, and p = 0.02, respectively). The prevalence of high blood pressure, diabetes mellitus, alcoholism, ischemic heart disease, and chronic heart failure was comparable between the two groups. The Charlson comorbidity index and HADS scores did not differ between the groups. CONCLUSIONS: Comorbidities are highly prevalent in COPD, regardless of its severity. Certain risk factors for CVD, themselves classified as diseases (including smoking, dyslipidemia, and depression), appear to be more prevalent in patients with mild-to-moderate COPD.
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spelling pubmed-55696102019-03-19 Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD Caram, Laura Miranda de Oliveira Ferrari, Renata Naves, Cristiane Roberta Coelho, Liana Sousa do Vale, Simone Alves Tanni, Suzana Erico Godoy, Irma J Bras Pneumol Original Article OBJECTIVE: To assess and compare the prevalence of comorbidities and risk factors for cardiovascular disease (CVD) in COPD patients according to disease severity. METHODS: The study included 25 patients with mild-to-moderate COPD (68% male; mean age, 65 ± 8 years; mean FEV(1), 73 ± 15% of predicted) and 25 with severe-to-very severe COPD (males, 56%; mean age, 69 ± 9 years; mean FEV(1), 40 ± 18% of predicted). Comorbidities were recorded on the basis of data obtained from medical charts and clinical evaluations. Comorbidities were registered on the basis of data obtained from medical charts and clinical evaluations. The Charlson comorbidity index was calculated, and the Hospital Anxiety and Depression Scale (HADS) score was determined. RESULTS: Of the 50 patients evaluated, 38 (76%) had been diagnosed with at least one comorbidity, 21 (42%) having been diagnosed with at least one CVD. Twenty-four patients (48%) had more than one CVD. Eighteen (36%) of the patients were current smokers, 10 (20%) had depression, 7 (14%) had dyslipidemia, and 7 (14%) had diabetes mellitus. Current smoking, depression, and dyslipidemia were more prevalent among the patients with mild-to-moderate COPD than among those with severe-to-very severe COPD (p < 0.001, p = 0.008, and p = 0.02, respectively). The prevalence of high blood pressure, diabetes mellitus, alcoholism, ischemic heart disease, and chronic heart failure was comparable between the two groups. The Charlson comorbidity index and HADS scores did not differ between the groups. CONCLUSIONS: Comorbidities are highly prevalent in COPD, regardless of its severity. Certain risk factors for CVD, themselves classified as diseases (including smoking, dyslipidemia, and depression), appear to be more prevalent in patients with mild-to-moderate COPD. Sociedade Brasileira de Pneumologia e Tisiologia 2016 /pmc/articles/PMC5569610/ /pubmed/27383930 http://dx.doi.org/10.1590/S1806-37562015000000121 Text en http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
Caram, Laura Miranda de Oliveira
Ferrari, Renata
Naves, Cristiane Roberta
Coelho, Liana Sousa
do Vale, Simone Alves
Tanni, Suzana Erico
Godoy, Irma
Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD
title Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD
title_full Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD
title_fullStr Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD
title_full_unstemmed Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD
title_short Risk factors for cardiovascular disease in patients with COPD: mild-to-moderate COPD versus severe-to-very severe COPD
title_sort risk factors for cardiovascular disease in patients with copd: mild-to-moderate copd versus severe-to-very severe copd
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569610/
https://www.ncbi.nlm.nih.gov/pubmed/27383930
http://dx.doi.org/10.1590/S1806-37562015000000121
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