Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria

Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated...

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Autores principales: Yeo, Tsin W., Florence, Salvatore M., Kalingonji, Ayam R., Chen, Youwei, Granger, Donald L., Anstey, Nicholas M., Mwaikambo, Esther D., Weinberg, J. Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569702/
https://www.ncbi.nlm.nih.gov/pubmed/28852670
http://dx.doi.org/10.1093/ofid/ofx079
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author Yeo, Tsin W.
Florence, Salvatore M.
Kalingonji, Ayam R.
Chen, Youwei
Granger, Donald L.
Anstey, Nicholas M.
Mwaikambo, Esther D.
Weinberg, J. Brice
author_facet Yeo, Tsin W.
Florence, Salvatore M.
Kalingonji, Ayam R.
Chen, Youwei
Granger, Donald L.
Anstey, Nicholas M.
Mwaikambo, Esther D.
Weinberg, J. Brice
author_sort Yeo, Tsin W.
collection PubMed
description Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), not SM (P = .06), children had increased oxygen consumption compared with controls.
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spelling pubmed-55697022017-08-29 Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria Yeo, Tsin W. Florence, Salvatore M. Kalingonji, Ayam R. Chen, Youwei Granger, Donald L. Anstey, Nicholas M. Mwaikambo, Esther D. Weinberg, J. Brice Open Forum Infect Dis Brief Report Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), not SM (P = .06), children had increased oxygen consumption compared with controls. Oxford University Press 2017-04-22 /pmc/articles/PMC5569702/ /pubmed/28852670 http://dx.doi.org/10.1093/ofid/ofx079 Text en © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Yeo, Tsin W.
Florence, Salvatore M.
Kalingonji, Ayam R.
Chen, Youwei
Granger, Donald L.
Anstey, Nicholas M.
Mwaikambo, Esther D.
Weinberg, J. Brice
Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria
title Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria
title_full Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria
title_fullStr Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria
title_full_unstemmed Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria
title_short Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria
title_sort decreased microvascular function in tanzanian children with severe and uncomplicated falciparum malaria
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569702/
https://www.ncbi.nlm.nih.gov/pubmed/28852670
http://dx.doi.org/10.1093/ofid/ofx079
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