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Prevention of Atrial Fibrillation by Using Sarcoplasmic Reticulum Calcium ATPase Pump Overexpression in a Rabbit Model of Rapid Atrial Pacing
BACKGROUND: Recent research suggests that abnormal Ca(2+) handling plays a role in the occurrence and maintenance of atrial fibrillation (AF). Therefore, Ca(2+) release and ingestion depend on properties of the ryanodine receptor (RyR) and sarcoplasmic reticulum Ca(2+)ATPase2a (SERCA2a). This study...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569926/ https://www.ncbi.nlm.nih.gov/pubmed/28811460 http://dx.doi.org/10.12659/MSM.904824 |