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Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules
Data produced with short-read sequencing technologies result in ambiguous haplotyping and a limited capacity to investigate the full repertoire of biologically relevant forms of genetic variation. The notion of haplotype-resolved sequencing data has recently gained traction to reduce this unwanted a...
Autores principales: | Redin, David, Borgström, Erik, He, Mengxiao, Aghelpasand, Hooman, Käller, Max, Ahmadian, Afshin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569991/ https://www.ncbi.nlm.nih.gov/pubmed/28525570 http://dx.doi.org/10.1093/nar/gkx436 |
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