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Droplet Barcode Sequencing for targeted linked-read haplotyping of single DNA molecules

Data produced with short-read sequencing technologies result in ambiguous haplotyping and a limited capacity to investigate the full repertoire of biologically relevant forms of genetic variation. The notion of haplotype-resolved sequencing data has recently gained traction to reduce this unwanted a...

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Detalles Bibliográficos
Autores principales: Redin, David, Borgström, Erik, He, Mengxiao, Aghelpasand, Hooman, Käller, Max, Ahmadian, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569991/
https://www.ncbi.nlm.nih.gov/pubmed/28525570
http://dx.doi.org/10.1093/nar/gkx436

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