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Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events
DNA nano-structures present appealing new means for monitoring different molecules. Here, we demonstrate the assembly and utilization of a surface-attached double-stranded DNA catenane composed of two intact interlinked DNA nano-circles for specific and sensitive measurements of the life essential t...
Autores principales: | Kristoffersen, Emil L., Givskov, Asger, Jørgensen, Line A., Jensen, Pia W., W. Byl, Jo Ann, Osheroff, Neil, Andersen, Anni H., Stougaard, Magnus, Ho, Yi-Ping, Knudsen, Birgitta R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570003/ https://www.ncbi.nlm.nih.gov/pubmed/28541438 http://dx.doi.org/10.1093/nar/gkx480 |
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