eIF1 modulates the recognition of suboptimal translation initiation sites and steers gene expression via uORFs

Alternative translation initiation mechanisms such as leaky scanning and reinitiation potentiate the polycistronic nature of human transcripts. By allowing for reprogrammed translation, these mechanisms can mediate biological responses to stimuli. We combined proteomics with ribosome profiling and m...

Descripción completa

Detalles Bibliográficos
Autores principales: Fijałkowska, Daria, Verbruggen, Steven, Ndah, Elvis, Jonckheere, Veronique, Menschaert, Gerben, Van Damme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570006/
https://www.ncbi.nlm.nih.gov/pubmed/28541577
http://dx.doi.org/10.1093/nar/gkx469

Ejemplares similares

Ejemplares similares