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Pathview Web: user friendly pathway visualization and data integration

Pathway analysis is widely used in omics studies. Pathway-based data integration and visualization is a critical component of the analysis. To address this need, we recently developed a novel R package called Pathview. Pathview maps, integrates and renders a large variety of biological data onto mol...

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Autores principales: Luo, Weijun, Pant, Gaurav, Bhavnasi, Yeshvant K., Blanchard, Steven G., Brouwer, Cory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570256/
https://www.ncbi.nlm.nih.gov/pubmed/28482075
http://dx.doi.org/10.1093/nar/gkx372
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author Luo, Weijun
Pant, Gaurav
Bhavnasi, Yeshvant K.
Blanchard, Steven G.
Brouwer, Cory
author_facet Luo, Weijun
Pant, Gaurav
Bhavnasi, Yeshvant K.
Blanchard, Steven G.
Brouwer, Cory
author_sort Luo, Weijun
collection PubMed
description Pathway analysis is widely used in omics studies. Pathway-based data integration and visualization is a critical component of the analysis. To address this need, we recently developed a novel R package called Pathview. Pathview maps, integrates and renders a large variety of biological data onto molecular pathway graphs. Here we developed the Pathview Web server, as to make pathway visualization and data integration accessible to all scientists, including those without the special computing skills or resources. Pathview Web features an intuitive graphical web interface and a user centered design. The server not only expands the core functions of Pathview, but also provides many useful features not available in the offline R package. Importantly, the server presents a comprehensive workflow for both regular and integrated pathway analysis of multiple omics data. In addition, the server also provides a RESTful API for programmatic access and conveniently integration in third-party software or workflows. Pathview Web is openly and freely accessible at https://pathview.uncc.edu/.
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spelling pubmed-55702562017-08-29 Pathview Web: user friendly pathway visualization and data integration Luo, Weijun Pant, Gaurav Bhavnasi, Yeshvant K. Blanchard, Steven G. Brouwer, Cory Nucleic Acids Res Web Server Issue Pathway analysis is widely used in omics studies. Pathway-based data integration and visualization is a critical component of the analysis. To address this need, we recently developed a novel R package called Pathview. Pathview maps, integrates and renders a large variety of biological data onto molecular pathway graphs. Here we developed the Pathview Web server, as to make pathway visualization and data integration accessible to all scientists, including those without the special computing skills or resources. Pathview Web features an intuitive graphical web interface and a user centered design. The server not only expands the core functions of Pathview, but also provides many useful features not available in the offline R package. Importantly, the server presents a comprehensive workflow for both regular and integrated pathway analysis of multiple omics data. In addition, the server also provides a RESTful API for programmatic access and conveniently integration in third-party software or workflows. Pathview Web is openly and freely accessible at https://pathview.uncc.edu/. Oxford University Press 2017-07-03 2017-05-08 /pmc/articles/PMC5570256/ /pubmed/28482075 http://dx.doi.org/10.1093/nar/gkx372 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Web Server Issue
Luo, Weijun
Pant, Gaurav
Bhavnasi, Yeshvant K.
Blanchard, Steven G.
Brouwer, Cory
Pathview Web: user friendly pathway visualization and data integration
title Pathview Web: user friendly pathway visualization and data integration
title_full Pathview Web: user friendly pathway visualization and data integration
title_fullStr Pathview Web: user friendly pathway visualization and data integration
title_full_unstemmed Pathview Web: user friendly pathway visualization and data integration
title_short Pathview Web: user friendly pathway visualization and data integration
title_sort pathview web: user friendly pathway visualization and data integration
topic Web Server Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570256/
https://www.ncbi.nlm.nih.gov/pubmed/28482075
http://dx.doi.org/10.1093/nar/gkx372
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