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Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas

BACKGROUND: Inhibitors of fibroblast growth factor receptors (FGFRs) have recently arisen as a promising treatment option for patients with FGFR alterations. Gene fusions involving FGFR3 and transforming acidic coiled-coil protein 3 (TACC3) have been detected in diffuse gliomas and other malignancie...

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Detalles Bibliográficos
Autores principales:	Granberg, Kirsi J, Annala, Matti, Lehtinen, Birgitta, Kesseli, Juha, Haapasalo, Joonas, Ruusuvuori, Pekka, Yli-Harja, Olli, Visakorpi, Tapio, Haapasalo, Hannu, Nykter, Matti, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570261/ https://www.ncbi.nlm.nih.gov/pubmed/28379477 http://dx.doi.org/10.1093/neuonc/nox028

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