Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels

Von Willebrand factor (VWF) is the carrier protein of the anti-haemophilic Factor VIII (FVIII) in plasma. It has been reported that the infusion of FVIII concentrate in haemophilia A patients results in lowered VWF plasma levels. However, the impact of F8-deficiency on VWF plasma levels in F8(-/y) m...

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Detalles Bibliográficos
Autores principales: Kiouptsi, Klytaimnistra, Grill, Alexandra, Mann, Amrit, Döhrmann, Mareike, Lillich, Maren, Jäckel, Sven, Malinarich, Frano, Formes, Henning, Manukyan, Davit, Subramaniam, Saravanan, Khandagale, Avinash, Karwot, Cornelia, Thal, Serge C., Bosmann, Markus, Scharrer, Inge, Jurk, Kerstin, Reinhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570278/
https://www.ncbi.nlm.nih.gov/pubmed/28837614
http://dx.doi.org/10.1371/journal.pone.0183590

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