A DNA inducing VLP vaccine designed for HIV and tested in mice

We developed a DNA vaccine that induces the formation of a VLP in vivo. This VLP was designed to elicit neutralizing antibodies, to induce better T-cell responses and to activate the innate immune system. Overall, 5 groups of 10 mice were electroporated with the following constructs: pVLP-LTR-GagPro...

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Detalles Bibliográficos
Autores principales: Calazans, Alexandre, Boggiano, Cesar, Lindsay, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570355/
https://www.ncbi.nlm.nih.gov/pubmed/28837706
http://dx.doi.org/10.1371/journal.pone.0183803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570355/
https://www.ncbi.nlm.nih.gov/pubmed/28837706
http://dx.doi.org/10.1371/journal.pone.0183803

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