Cargando…
Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems
One important aim in cell culture-based viral vaccine and vector production is the implementation of continuous processes. Such a development has the potential to reduce costs of vaccine manufacturing as volumetric productivity is increased and the manufacturing footprint is reduced. In this work, c...
Autores principales: | Tapia, Felipe, Jordan, Ingo, Genzel, Yvonne, Reichl, Udo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570375/ https://www.ncbi.nlm.nih.gov/pubmed/28837572 http://dx.doi.org/10.1371/journal.pone.0182553 |
Ejemplares similares
-
Elements in the Development of a Production Process for Modified Vaccinia Virus Ankara
por: Jordan, Ingo, et al.
Publicado: (2013) -
Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production
por: Gränicher, Gwendal, et al.
Publicado: (2020) -
Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the “von Magnus effect”
por: Tapia, Felipe, et al.
Publicado: (2019) -
Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production
por: Tapia, Felipe, et al.
Publicado: (2016) -
High-cell-density cultivations to increase MVA virus production
por: Vázquez-Ramírez, Daniel, et al.
Publicado: (2018)