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Subcellular Distribution of S-Nitrosylated H-Ras in Differentiated and Undifferentiated PC12 Cells during Hypoxia

OBJECTIVE: Hypoxia or exposure to excessive reactive oxygen or nitrogen species could induce S-nitrosylation of various target proteins, including GTPases of the Ras-superfamily. Under hypoxic conditions, the Ras-protein is translocated to the cytosol and interacts with the Golgi complex, endoplasmi...

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Detalles Bibliográficos
Autores principales: Barbakadze, Tamar, Goloshvili, Galina, Narmania, Nana, Zhuravliova, Elene, Mikeladze, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570409/
https://www.ncbi.nlm.nih.gov/pubmed/28836406