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Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha

The GW182/TNRC6 family of proteins are central scaffolds that link microRNA-associated Argonaute proteins to the cytoplasmic decay machinery for targeted mRNA degradation processes. Although nuclear roles for the GW182/TNRC6 proteins are unknown, recent reports have demonstrated nucleocytoplasmic sh...

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Detalles Bibliográficos
Autores principales:	Chaston, Jessica J., Stewart, Alastair Gordon, Christie, Mary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570423/ https://www.ncbi.nlm.nih.gov/pubmed/28837617 http://dx.doi.org/10.1371/journal.pone.0183587

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