Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance

High CD44 expression is associated with enhanced malignant potential in esophageal squamous cell carcinoma (ESCC), amongst the deadliest of all human carcinomas. Although alterations in autophagy and CD44 expression are associated with poor patient outcomes in various cancer types, the relationship...

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Detalles Bibliográficos
Autores principales: Whelan, Kelly A., Chandramouleeswaran, Prasanna M., Tanaka, Koji, Natsuizaka, Mitsuteru, Guha, Manti, Srinivasan, Satish, Darling, Douglas S., Kita, Yoshiaki, Natsugoe, Shoji, Winkler, Jeffrey D., Klein-Szanto, Andres J., Amaravadi, Ravi K., Avadhani, Narayan G., Rustgi, Anil. K, Nakagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570661/
https://www.ncbi.nlm.nih.gov/pubmed/28414310
http://dx.doi.org/10.1038/onc.2017.102

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