Transgenic Mice Overexpressing the Divalent Metal Transporter 1 Exhibit Iron Accumulation and Enhanced Parkin Expression in the Brain

Exposure to divalent metals such as iron and manganese is thought to increase the risk for Parkinson’s disease (PD). Under normal circumstances, cellular iron and manganese uptake is regulated by the divalent metal transporter 1 (DMT1). Accordingly, alterations in DMT1 levels may underlie the abnorm...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng-Wu, Tai, Yee Kit, Chai, Bing-Han, Chew, Katherine C. M., Ang, Eng-Tat, Tsang, Fai, Tan, Bryce W. Q., Hong, Eugenia T. E., Asad, Abu Bakar Ali, Chuang, Kai-Hsiang, Lim, Kah-Leong, Soong, Tuck Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570798/
https://www.ncbi.nlm.nih.gov/pubmed/28695462
http://dx.doi.org/10.1007/s12017-017-8451-0

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