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Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation
Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, and its causes remain unknown. A major hallmark of the disease is the increasing presence of aggregated alpha-synuclein (aSyn). Furthermore, there is a solid consensus on iron (Fe) accumulation in several regions of PD...
Autores principales: | Carboni, Eleonora, Tatenhorst, Lars, Tönges, Lars, Barski, Elisabeth, Dambeck, Vivian, Bähr, Mathias, Lingor, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570801/ https://www.ncbi.nlm.nih.gov/pubmed/28623611 http://dx.doi.org/10.1007/s12017-017-8447-9 |
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