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The epigenetic modifier Fam208a is required to maintain epiblast cell fitness
Gastrulation initiates with the formation of the primitive streak, during which, cells of the epiblast delaminate to form the mesoderm and definitive endoderm. At this stage, the pluripotent cell population of the epiblast undergoes very rapid proliferation and extensive epigenetic programming. Here...
Autores principales: | Bhargava, Shohag, Cox, Brian, Polydorou, Christiana, Gresakova, Veronika, Korinek, Vladimir, Strnad, Hynek, Sedlacek, Radislav, Epp, Trevor Allan, Chawengsaksophak, Kallayanee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570896/ https://www.ncbi.nlm.nih.gov/pubmed/28839193 http://dx.doi.org/10.1038/s41598-017-09490-w |
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