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The epigenetic modifier Fam208a is required to maintain epiblast cell fitness

Gastrulation initiates with the formation of the primitive streak, during which, cells of the epiblast delaminate to form the mesoderm and definitive endoderm. At this stage, the pluripotent cell population of the epiblast undergoes very rapid proliferation and extensive epigenetic programming. Here...

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Detalles Bibliográficos
Autores principales: Bhargava, Shohag, Cox, Brian, Polydorou, Christiana, Gresakova, Veronika, Korinek, Vladimir, Strnad, Hynek, Sedlacek, Radislav, Epp, Trevor Allan, Chawengsaksophak, Kallayanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570896/
https://www.ncbi.nlm.nih.gov/pubmed/28839193
http://dx.doi.org/10.1038/s41598-017-09490-w

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