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Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer
The origin and evolution of land plants was an important event in the history of life and initiated the establishment of modern terrestrial ecosystems. From water to terrestrial environments, plants needed to overcome the enhanced ultraviolet (UV) radiation and many other DNA-damaging agents. Evolvi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570899/ https://www.ncbi.nlm.nih.gov/pubmed/28839126 http://dx.doi.org/10.1038/s41598-017-05066-w |
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author | Fang, Huimin Huangfu, Liexiang Chen, Rujia Li, Pengcheng Xu, Shuhui Zhang, Enying Cao, Wei Liu, Li Yao, Youli Liang, Guohua Xu, Chenwu Zhou, Yong Yang, Zefeng |
author_facet | Fang, Huimin Huangfu, Liexiang Chen, Rujia Li, Pengcheng Xu, Shuhui Zhang, Enying Cao, Wei Liu, Li Yao, Youli Liang, Guohua Xu, Chenwu Zhou, Yong Yang, Zefeng |
author_sort | Fang, Huimin |
collection | PubMed |
description | The origin and evolution of land plants was an important event in the history of life and initiated the establishment of modern terrestrial ecosystems. From water to terrestrial environments, plants needed to overcome the enhanced ultraviolet (UV) radiation and many other DNA-damaging agents. Evolving new genes with the function of DNA repair is critical for the origin and radiation of land plants. In bacteria, the DNA-3-methyladenine glycosylase (MAG) recognizes of a variety of base lesions and initiates the process of the base excision repair for damaged DNA. The homologs of MAG gene are present in all major lineages of streptophytes, and both the phylogenic and sequence similarity analyses revealed that green plant MAG gene originated through an ancient horizontal gene transfer (HGT) event from bacteria. Experimental evidence demonstrated that the expression of the maize ZmMAG gene was induced by UV and zeocin, both of which are known as DNA-damaging agents. Further investigation revealed that Streptophyta MAG genes had undergone positive selection during the initial evolutionary period in the ancestor of land plants. Our findings demonstrated that the ancient HGT of MAG to the ancestor of land plants probably played an important role in preadaptation to DNA-damaging agents in terrestrial environments. |
format | Online Article Text |
id | pubmed-5570899 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55708992017-09-01 Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer Fang, Huimin Huangfu, Liexiang Chen, Rujia Li, Pengcheng Xu, Shuhui Zhang, Enying Cao, Wei Liu, Li Yao, Youli Liang, Guohua Xu, Chenwu Zhou, Yong Yang, Zefeng Sci Rep Article The origin and evolution of land plants was an important event in the history of life and initiated the establishment of modern terrestrial ecosystems. From water to terrestrial environments, plants needed to overcome the enhanced ultraviolet (UV) radiation and many other DNA-damaging agents. Evolving new genes with the function of DNA repair is critical for the origin and radiation of land plants. In bacteria, the DNA-3-methyladenine glycosylase (MAG) recognizes of a variety of base lesions and initiates the process of the base excision repair for damaged DNA. The homologs of MAG gene are present in all major lineages of streptophytes, and both the phylogenic and sequence similarity analyses revealed that green plant MAG gene originated through an ancient horizontal gene transfer (HGT) event from bacteria. Experimental evidence demonstrated that the expression of the maize ZmMAG gene was induced by UV and zeocin, both of which are known as DNA-damaging agents. Further investigation revealed that Streptophyta MAG genes had undergone positive selection during the initial evolutionary period in the ancestor of land plants. Our findings demonstrated that the ancient HGT of MAG to the ancestor of land plants probably played an important role in preadaptation to DNA-damaging agents in terrestrial environments. Nature Publishing Group UK 2017-08-24 /pmc/articles/PMC5570899/ /pubmed/28839126 http://dx.doi.org/10.1038/s41598-017-05066-w Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Fang, Huimin Huangfu, Liexiang Chen, Rujia Li, Pengcheng Xu, Shuhui Zhang, Enying Cao, Wei Liu, Li Yao, Youli Liang, Guohua Xu, Chenwu Zhou, Yong Yang, Zefeng Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer |
title | Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer |
title_full | Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer |
title_fullStr | Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer |
title_full_unstemmed | Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer |
title_short | Ancestor of land plants acquired the DNA-3-methyladenine glycosylase (MAG) gene from bacteria through horizontal gene transfer |
title_sort | ancestor of land plants acquired the dna-3-methyladenine glycosylase (mag) gene from bacteria through horizontal gene transfer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570899/ https://www.ncbi.nlm.nih.gov/pubmed/28839126 http://dx.doi.org/10.1038/s41598-017-05066-w |
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