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Polymyxin B containing polyion complex (PIC) nanoparticles: Improving the antimicrobial activity by tailoring the degree of polymerisation of the inert component

Here, we describe the preparation and characterisation of polyion complex (PIC) nanoparticles containing last resort antimicrobial polymyxin B (Pol-B). PIC nanoparticles were prepared with poly(styrene sulphonate) (PSS) as an inert component, across a range of degrees of polymerisation to evaluate t...

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Detalles Bibliográficos
Autores principales: Insua, Ignacio, Zizmare, Laimdota, Peacock, Anna F. A., Krachler, Anne Marie, Fernandez-Trillo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570901/
https://www.ncbi.nlm.nih.gov/pubmed/28839223
http://dx.doi.org/10.1038/s41598-017-09667-3