An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network

The ubiquitination mediated by ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2), and ubiquitin ligase (E3) cascade is crucial to protein degradation, transcription regulation, and cell signaling in eukaryotic cells. The high specificity of ubiquitination is regulated by the intera...

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Detalles Bibliográficos
Autores principales: Li, Yang, Xie, Ping, Lu, Liang, Wang, Jian, Diao, Lihong, Liu, Zhongyang, Guo, Feifei, He, Yangzhige, Liu, Yuan, Huang, Qin, Liang, Han, Li, Dong, He, Fuchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570908/
https://www.ncbi.nlm.nih.gov/pubmed/28839186
http://dx.doi.org/10.1038/s41467-017-00299-9

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