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Optogenetic regulation of insulin secretion in pancreatic β-cells
Pancreatic β-cell insulin production is orchestrated by a complex circuitry involving intracellular elements including cyclic AMP (cAMP). Tackling aberrations in glucose-stimulated insulin release such as in diabetes with pharmacological agents, which boost the secretory capacity of β-cells, is link...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571193/ https://www.ncbi.nlm.nih.gov/pubmed/28839233 http://dx.doi.org/10.1038/s41598-017-09937-0 |