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Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias

Each year more than 7 million people die from cardiac arrhythmias. Yet no robust solution exists today to detect such heart anomalies right at the moment they occur. The purpose of this study was to design a personalized health monitoring system that can detect early occurrences of arrhythmias from...

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Detalles Bibliográficos
Autores principales: Kiranyaz, Serkan, Ince, Turker, Gabbouj, Moncef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571226/
https://www.ncbi.nlm.nih.gov/pubmed/28839215
http://dx.doi.org/10.1038/s41598-017-09544-z
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author Kiranyaz, Serkan
Ince, Turker
Gabbouj, Moncef
author_facet Kiranyaz, Serkan
Ince, Turker
Gabbouj, Moncef
author_sort Kiranyaz, Serkan
collection PubMed
description Each year more than 7 million people die from cardiac arrhythmias. Yet no robust solution exists today to detect such heart anomalies right at the moment they occur. The purpose of this study was to design a personalized health monitoring system that can detect early occurrences of arrhythmias from an individual’s electrocardiogram (ECG) signal. We first modelled the common causes of arrhythmias in the signal domain as a degradation of normal ECG beats to abnormal beats. Using the degradation models, we performed abnormal beat synthesis which created potential abnormal beats from the average normal beat of the individual. Finally, a Convolutional Neural Network (CNN) was trained using real normal and synthesized abnormal beats. As a personalized classifier, the trained CNN can monitor ECG beats in real time for arrhythmia detection. Over 34 patients’ ECG records with a total of 63,341 ECG beats from the MIT-BIH arrhythmia benchmark database, we have shown that the probability of detecting one or more abnormal ECG beats among the first three occurrences is higher than 99.4% with a very low false-alarm rate.
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spelling pubmed-55712262017-09-01 Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias Kiranyaz, Serkan Ince, Turker Gabbouj, Moncef Sci Rep Article Each year more than 7 million people die from cardiac arrhythmias. Yet no robust solution exists today to detect such heart anomalies right at the moment they occur. The purpose of this study was to design a personalized health monitoring system that can detect early occurrences of arrhythmias from an individual’s electrocardiogram (ECG) signal. We first modelled the common causes of arrhythmias in the signal domain as a degradation of normal ECG beats to abnormal beats. Using the degradation models, we performed abnormal beat synthesis which created potential abnormal beats from the average normal beat of the individual. Finally, a Convolutional Neural Network (CNN) was trained using real normal and synthesized abnormal beats. As a personalized classifier, the trained CNN can monitor ECG beats in real time for arrhythmia detection. Over 34 patients’ ECG records with a total of 63,341 ECG beats from the MIT-BIH arrhythmia benchmark database, we have shown that the probability of detecting one or more abnormal ECG beats among the first three occurrences is higher than 99.4% with a very low false-alarm rate. Nature Publishing Group UK 2017-08-24 /pmc/articles/PMC5571226/ /pubmed/28839215 http://dx.doi.org/10.1038/s41598-017-09544-z Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Kiranyaz, Serkan
Ince, Turker
Gabbouj, Moncef
Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias
title Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias
title_full Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias
title_fullStr Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias
title_full_unstemmed Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias
title_short Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias
title_sort personalized monitoring and advance warning system for cardiac arrhythmias
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571226/
https://www.ncbi.nlm.nih.gov/pubmed/28839215
http://dx.doi.org/10.1038/s41598-017-09544-z
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