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Hepatitis C Virus Strain-Dependent Usage of Apolipoprotein E Modulates Assembly Efficiency and Specific Infectivity of Secreted Virions

Hepatitis C virus (HCV) is extraordinarily diverse and uses entry factors in a strain-specific manner. Virus particles associate with lipoproteins, and apolipoprotein E (ApoE) is critical for HCV assembly and infectivity. However, whether ApoE dependency is common to all HCV genotypes remains unknow...

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Detalles Bibliográficos
Autores principales:	Weller, Romy, Hueging, Kathrin, Brown, Richard J. P., Todt, Daniel, Joecks, Sebastian, Vondran, Florian W. R., Pietschmann, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Structure and Assembly
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571276/ https://www.ncbi.nlm.nih.gov/pubmed/28659481 http://dx.doi.org/10.1128/JVI.00422-17

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