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Comparison of Omadacycline and Tigecycline Pharmacokinetics in the Plasma, Epithelial Lining Fluid, and Alveolar Cells of Healthy Adult Subjects

The steady-state concentrations of omadacycline and tigecycline in the plasma, epithelial lining fluid (ELF), and alveolar cells (AC) of 58 healthy adult subjects were obtained. Subjects were administered either omadacycline at 100 mg intravenously (i.v.) every 12 h for two doses followed by 100 mg...

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Detalles Bibliográficos
Autores principales:	Gotfried, Mark H., Horn, Karolyn, Garrity-Ryan, Lynne, Villano, Stephen, Tzanis, Evan, Chitra, Surya, Manley, Amy, Tanaka, S. Ken, Rodvold, Keith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571291/ https://www.ncbi.nlm.nih.gov/pubmed/28696233 http://dx.doi.org/10.1128/AAC.01135-17

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