Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck

An H4N6 subtype avian influenza virus was isolated from a pockmark duck in southern China in November 2013 and named A/duck/Guangxi/149D24/2013 (H4N6). All eight gene segments of the strain were sequenced. Sequence analysis indicated that this H4N6 virus was a natural reassortant virus. This H4N6 vi...

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Autores principales: Xie, Liji, Xie, Zhixun, Wu, Aiqiong, Luo, Sisi, Zhang, Minxiu, Huang, Li, Xie, Zhiqin, Huang, Jiaoling, Zhang, Yanfang, Zeng, Tingting, Deng, Xianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571406/
https://www.ncbi.nlm.nih.gov/pubmed/28839020
http://dx.doi.org/10.1128/genomeA.00802-17
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author Xie, Liji
Xie, Zhixun
Wu, Aiqiong
Luo, Sisi
Zhang, Minxiu
Huang, Li
Xie, Zhiqin
Huang, Jiaoling
Zhang, Yanfang
Zeng, Tingting
Deng, Xianwen
author_facet Xie, Liji
Xie, Zhixun
Wu, Aiqiong
Luo, Sisi
Zhang, Minxiu
Huang, Li
Xie, Zhiqin
Huang, Jiaoling
Zhang, Yanfang
Zeng, Tingting
Deng, Xianwen
author_sort Xie, Liji
collection PubMed
description An H4N6 subtype avian influenza virus was isolated from a pockmark duck in southern China in November 2013 and named A/duck/Guangxi/149D24/2013 (H4N6). All eight gene segments of the strain were sequenced. Sequence analysis indicated that this H4N6 virus was a natural reassortant virus. This H4N6 virus has two basic amino acids in the cleavage site of hemagglutinin 1 (HA1) and HA2, and the amino acid motif of cleavage site was PEKASRGLF, which is the typical characteristic of the low-pathogenic avian influenza virus. This study will help understand the epidemiology and molecular characteristics of avian influenza virus in pockmark ducks.
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spelling pubmed-55714062017-08-31 Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck Xie, Liji Xie, Zhixun Wu, Aiqiong Luo, Sisi Zhang, Minxiu Huang, Li Xie, Zhiqin Huang, Jiaoling Zhang, Yanfang Zeng, Tingting Deng, Xianwen Genome Announc Viruses An H4N6 subtype avian influenza virus was isolated from a pockmark duck in southern China in November 2013 and named A/duck/Guangxi/149D24/2013 (H4N6). All eight gene segments of the strain were sequenced. Sequence analysis indicated that this H4N6 virus was a natural reassortant virus. This H4N6 virus has two basic amino acids in the cleavage site of hemagglutinin 1 (HA1) and HA2, and the amino acid motif of cleavage site was PEKASRGLF, which is the typical characteristic of the low-pathogenic avian influenza virus. This study will help understand the epidemiology and molecular characteristics of avian influenza virus in pockmark ducks. American Society for Microbiology 2017-08-24 /pmc/articles/PMC5571406/ /pubmed/28839020 http://dx.doi.org/10.1128/genomeA.00802-17 Text en Copyright © 2017 Xie et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Viruses
Xie, Liji
Xie, Zhixun
Wu, Aiqiong
Luo, Sisi
Zhang, Minxiu
Huang, Li
Xie, Zhiqin
Huang, Jiaoling
Zhang, Yanfang
Zeng, Tingting
Deng, Xianwen
Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck
title Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck
title_full Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck
title_fullStr Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck
title_full_unstemmed Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck
title_short Genetic Characterization of an Avian Influenza Virus H4N6 Strain Isolated from a Guangxi Pockmark Duck
title_sort genetic characterization of an avian influenza virus h4n6 strain isolated from a guangxi pockmark duck
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571406/
https://www.ncbi.nlm.nih.gov/pubmed/28839020
http://dx.doi.org/10.1128/genomeA.00802-17
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