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Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi

INTRODUCTION: Pneumococcal infections cause a high death toll in Sub Saharan Africa (SSA) but the recently rolled out pneumococcal conjugate vaccines (PCV) will reduce the disease burden. To better understand the population impact of these vaccines, comprehensive analysis of large collections of pne...

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Detalles Bibliográficos
Autores principales: Chaguza, Chrispin, Cornick, Jennifer E., Andam, Cheryl P., Gladstone, Rebecca A., Alaerts, Maaike, Musicha, Patrick, Peno, Chikondi, Bar-Zeev, Naor, Kamng'ona, Arox W., Kiran, Anmol M., Msefula, Chisomo L., McGee, Lesley, Breiman, Robert F., Kadioglu, Aras, French, Neil, Heyderman, Robert S., Hanage, William P., Bentley, Stephen D., Everett, Dean B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571440/
https://www.ncbi.nlm.nih.gov/pubmed/28711389
http://dx.doi.org/10.1016/j.vaccine.2017.07.009

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