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miR‐495 sensitizes MDR cancer cells to the combination of doxorubicin and taxol by inhibiting MDR1 expression

MDR1 is highly expressed in MDR A2780DX5 ovarian cancer cells, MDR SGC7901R gastric cancer cells and recurrent tumours. It pumps cytoplasmic agents out of cells, leading to decreased drug accumulation in cells and making cancer cells susceptible to multidrug resistance. Here, we identified that miR‐...

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Detalles Bibliográficos
Autores principales: Zou, Zhenyou, Zou, Ruyi, Zong, Dan, Shi, Yonghong, Chen, Jinyao, Huang, Jie, Zhu, Jiahui, Chen, Liguan, Bao, Xiaoyan, Liu, Yuan, Liu, Weihao, Huang, Wenhui, Hu, Jingsang, Chen, Zhi, Lao, Xiaojie, Chen, Chaoqun, Huang, Xiaoli, Lu, Yao, Ni, Xueyin, Fang, Daoquan, Wu, Dengqiang, Lu, Shuangshuang, Jiang, Mingzhu, Qiu, Chenyang, Wu, Yuya, Qiu, Qisha, Dong, Yanyuan, Su, Yangyang, Zhao, Chenmin, Zhong, Zhihe, Cai, Jing, Liang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571520/
https://www.ncbi.nlm.nih.gov/pubmed/28411377
http://dx.doi.org/10.1111/jcmm.13114