Mitochondrial PKC‐ε deficiency promotes I/R‐mediated myocardial injury via GSK3β‐dependent mitochondrial permeability transition pore opening

Mitochondrial fission is critically involved in cardiomyocyte apoptosis, which has been considered as one of the leading causes of ischaemia/reperfusion (I/R)‐induced myocardial injury. In our previous works, we demonstrate that aldehyde dehydrogenase‐2 (ALDH2) deficiency aggravates cardiomyocyte ap...

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Detalles Bibliográficos
Autores principales: Wang, Shijun, Zhang, Feng, Zhao, Gang, Cheng, Yong, Wu, Ting, Wu, Bing, Zhang, You‐en
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571523/
https://www.ncbi.nlm.nih.gov/pubmed/28266127
http://dx.doi.org/10.1111/jcmm.13121

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