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Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate

Neuroblastoma is the most common extracranial solid tumour of infancy. Pathological activation of glucose consumption, glycolysis and glycolysis‐activating Akt kinase occur frequently in neuroblastoma cells, and these changes correlate with poor prognosis of patients. Therefore, several inhibitors o...

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Detalles Bibliográficos
Autores principales: Navrátilová, Jarmila, Karasová, Martina, Kohutková Lánová, Martina, Jiráková, Ludmila, Budková, Zuzana, Pacherník, Jiří, Šmarda, Jan, Beneš, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571524/
https://www.ncbi.nlm.nih.gov/pubmed/28244639
http://dx.doi.org/10.1111/jcmm.13106