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Selective elimination of neuroblastoma cells by synergistic effect of Akt kinase inhibitor and tetrathiomolybdate
Neuroblastoma is the most common extracranial solid tumour of infancy. Pathological activation of glucose consumption, glycolysis and glycolysis‐activating Akt kinase occur frequently in neuroblastoma cells, and these changes correlate with poor prognosis of patients. Therefore, several inhibitors o...
Autores principales: | Navrátilová, Jarmila, Karasová, Martina, Kohutková Lánová, Martina, Jiráková, Ludmila, Budková, Zuzana, Pacherník, Jiří, Šmarda, Jan, Beneš, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571524/ https://www.ncbi.nlm.nih.gov/pubmed/28244639 http://dx.doi.org/10.1111/jcmm.13106 |
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