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Processing and secretion of guanylate binding protein‐1 depend on inflammatory caspase activity

Human guanylate binding protein‐1 (GBP‐1) belongs to the family of large GTPases. The expression of GBP‐1 is inducible by inflammatory cytokines, and the protein is involved in inflammatory processes and host defence against cellular pathogens. GBP‐1 is the first GTPase which was described to be sec...

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Detalles Bibliográficos
Autores principales: Naschberger, Elisabeth, Geißdörfer, Walter, Bogdan, Christian, Tripal, Philipp, Kremmer, Elisabeth, Stürzl, Michael, Britzen‐Laurent, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571548/
https://www.ncbi.nlm.nih.gov/pubmed/28272793
http://dx.doi.org/10.1111/jcmm.13116