Reduced expression of let‐7f activates TGF‐β/ALK5 pathway and leads to impaired ischaemia‐induced neovascularization after cigarette smoke exposure

This study sought to determine the potential role of microRNAs (miRNAs) in the detrimental effects of cigarette smoke on angiogenesis and neovascularization. Using large‐scale miRNA profiling and qRT‐PCR analyses, we identified let‐7f as a pro‐angiogenic miRNA which expression is significantly reduc...

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Detalles Bibliográficos
Autores principales: Dhahri, Wahiba, Dussault, Sylvie, Haddad, Paola, Turgeon, Julie, Tremblay, Sophie, Rolland, Kevin, Desjarlais, Michel, Cáceres‐Gorriti, Katia Y, Mathieu, Raphael, Rivard, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571564/
https://www.ncbi.nlm.nih.gov/pubmed/28345812
http://dx.doi.org/10.1111/jcmm.13144

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