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Probing the compartmentalization of HIV-1 in the central nervous system through its neutralization properties

Compartmentalization of HIV-1 has been observed in the cerebrospinal fluid (CSF) of patients at different clinical stages. Considering the low permeability of the blood-brain barrier, we wondered if a reduced selective pressure by neutralizing antibodies (NAb) in the central nervous system (CNS) cou...

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Detalles Bibliográficos
Autores principales: Stefic, Karl, Chaillon, Antoine, Bouvin-Pley, Mélanie, Moreau, Alain, Braibant, Martine, Bastides, Frédéric, Gras, Guillaume, Bernard, Louis, Barin, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571919/
https://www.ncbi.nlm.nih.gov/pubmed/28841647
http://dx.doi.org/10.1371/journal.pone.0181680