Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics

BACKGROUND: While a subgroup of patients with exacerbations of chronic obstructive pulmonary disease (COPD) clearly benefit from antibiotics, their identification remains challenging. We hypothesised that selective assessment of the balance between the two dominant bacterial groups (Gammaproteobacte...

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Detalles Bibliográficos
Autores principales: Haldar, Koirobi, Bafadhel, Mona, Lau, Kelvin, Berg, Adam, Kwambana, Brenda, Kebadze, Tatiana, Ramsheh, Mohammadali Yavari, Barker, Bethan, Haldar, Pranabashis, Johnston, Sebastian, Ketley, Julian M., Brightling, Christopher E., Barer, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571965/
https://www.ncbi.nlm.nih.gov/pubmed/28841671
http://dx.doi.org/10.1371/journal.pone.0182833

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