CHOP favors endoplasmic reticulum stress-induced apoptosis in hepatocellular carcinoma cells via inhibition of autophagy

C/EBP-homologous protein (CHOP) is an important component of the endoplasmic reticulum (ER) stress response. We demonstrated the induction of ER stress in response to tunicamycin stimulation, as evidenced by increased expression of chaperone proteins Grp78, Grp94, and enhanced eukaryotic initiation...

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Detalles Bibliográficos
Autores principales: Lei, Yan, Wang, Shuiliang, Ren, Bingshuang, Wang, Jin, Chen, Jin, Lu, Jun, Zhan, Shihuai, Fu, Yunfeng, Huang, Lianghu, Tan, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571976/
https://www.ncbi.nlm.nih.gov/pubmed/28841673
http://dx.doi.org/10.1371/journal.pone.0183680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571976/
https://www.ncbi.nlm.nih.gov/pubmed/28841673
http://dx.doi.org/10.1371/journal.pone.0183680

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