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Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms

Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-as...

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Autores principales: Qin, Feiyun, Li, Zhenbao, Fang, Xinggen, Zhao, Xintong, Liu, Jiaqiang, Wu, Degang, Lai, Niansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572012/
https://www.ncbi.nlm.nih.gov/pubmed/28834890
http://dx.doi.org/10.1097/MD.0000000000007832
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author Qin, Feiyun
Li, Zhenbao
Fang, Xinggen
Zhao, Xintong
Liu, Jiaqiang
Wu, Degang
Lai, Niansheng
author_facet Qin, Feiyun
Li, Zhenbao
Fang, Xinggen
Zhao, Xintong
Liu, Jiaqiang
Wu, Degang
Lai, Niansheng
author_sort Qin, Feiyun
collection PubMed
description Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embolization of very small ruptured intracranial aneurysms. We retrospectively reviewed the clinical and imaging data from 37 patients with very small ruptured intracranial aneurysms who had SAC using Enterprise stents performed from February 2012 to July 2016 in our department. Data collected and analyzed included patient demographics, morphologic features of the aneurysm, treatment results, and follow-up results. Clinical outcomes were evaluated by the Glasgow Outcome Scale (GOS). Enterprise stents were successfully implanted in all 37 patients with very small ruptured intracranial aneurysms. Of the 37 individuals, 28 patients exhibited complete occlusion at Raymond grade I, 5 patients exhibited occlusion at Raymond grade II, and 4 patients at Raymond grade III. Procedure-related complications occurred in 3 of 37 patients (8.1%), including 1 case of intraprocedure aneurysm rupture who died from cerebral herniation caused by severe postoperative cerebral ischemia during the hospital stay, and the other 2 complications were acute in-stent thrombosis, and occlusion of parent artery caused by falling-off internal carotid artery plaque, respectively. A total of 36 patients underwent postoperative clinical follow-up visits for 6 to 24 months of which 31 patients recovered (GOS ≥ 4). One patient had hemiplegic paralysis, and no rehemorrhage was found. A total of 25 patients underwent follow-up digital subtraction angiography (DSA) at 3–21 months postintervention, in whom there were 22 cases with complete occlusion, 2 cases with recurrence of aneurysm neck, and 1 case with in-stent restenosis, but there was no patient with neurologic deficits. The Enterprise stent-assisted coiling embolization can be a safe and effective technique for treatment of very small ruptured intracranial aneurysms.
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spelling pubmed-55720122017-09-06 Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms Qin, Feiyun Li, Zhenbao Fang, Xinggen Zhao, Xintong Liu, Jiaqiang Wu, Degang Lai, Niansheng Medicine (Baltimore) 7100 Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embolization of very small ruptured intracranial aneurysms. We retrospectively reviewed the clinical and imaging data from 37 patients with very small ruptured intracranial aneurysms who had SAC using Enterprise stents performed from February 2012 to July 2016 in our department. Data collected and analyzed included patient demographics, morphologic features of the aneurysm, treatment results, and follow-up results. Clinical outcomes were evaluated by the Glasgow Outcome Scale (GOS). Enterprise stents were successfully implanted in all 37 patients with very small ruptured intracranial aneurysms. Of the 37 individuals, 28 patients exhibited complete occlusion at Raymond grade I, 5 patients exhibited occlusion at Raymond grade II, and 4 patients at Raymond grade III. Procedure-related complications occurred in 3 of 37 patients (8.1%), including 1 case of intraprocedure aneurysm rupture who died from cerebral herniation caused by severe postoperative cerebral ischemia during the hospital stay, and the other 2 complications were acute in-stent thrombosis, and occlusion of parent artery caused by falling-off internal carotid artery plaque, respectively. A total of 36 patients underwent postoperative clinical follow-up visits for 6 to 24 months of which 31 patients recovered (GOS ≥ 4). One patient had hemiplegic paralysis, and no rehemorrhage was found. A total of 25 patients underwent follow-up digital subtraction angiography (DSA) at 3–21 months postintervention, in whom there were 22 cases with complete occlusion, 2 cases with recurrence of aneurysm neck, and 1 case with in-stent restenosis, but there was no patient with neurologic deficits. The Enterprise stent-assisted coiling embolization can be a safe and effective technique for treatment of very small ruptured intracranial aneurysms. Wolters Kluwer Health 2017-08-25 /pmc/articles/PMC5572012/ /pubmed/28834890 http://dx.doi.org/10.1097/MD.0000000000007832 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0
spellingShingle 7100
Qin, Feiyun
Li, Zhenbao
Fang, Xinggen
Zhao, Xintong
Liu, Jiaqiang
Wu, Degang
Lai, Niansheng
Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
title Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
title_full Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
title_fullStr Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
title_full_unstemmed Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
title_short Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
title_sort therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572012/
https://www.ncbi.nlm.nih.gov/pubmed/28834890
http://dx.doi.org/10.1097/MD.0000000000007832
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