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Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients

BACKGROUND: Predictive biomarkers or signature(s) for oesophageal cancer (OC) patients undergoing preoperative therapy could help administration of effective therapy, avoidance of ineffective ones, and establishment new strategies. Since the hedgehog pathway is often upregulated in OC, we examined i...

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Detalles Bibliográficos
Autores principales: Wadhwa, Roopma, Wang, Xuemei, Baladandayuthapani, Veerabhadran, Liu, Bin, Shiozaki, Hironori, Shimodaira, Yusuke, Lin, Quan, Elimova, Elena, Hofstetter, Wayne L, Swisher, Stephen G, Rice, David C, Maru, Dipen M, Kalhor, Neda, Bhutani, Manoop S, Weston, Brian, Lee, Jeffrey H, Skinner, Heath D, Scott, Ailing W, Kaya, Dilsa Mizrak, Harada, Kazuto, Berry, Donald, Song, Shumei, Ajani, Jaffer A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572179/
https://www.ncbi.nlm.nih.gov/pubmed/28728163
http://dx.doi.org/10.1038/bjc.2017.225