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The Influence of Regional Distribution and Pharmacologic Specificity of GABA(A)R Subtype Expression on Anesthesia and Emergence

Anesthetics produce unconsciousness by modulating ion channels that control neuronal excitability. Research has shown that specific GABA(A) receptor (GABA(A)R) subtypes in particular regions of the central nervous system contribute to different hyperpolarizing conductances, and behaviorally to disti...

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Detalles Bibliográficos
Autores principales: Speigel, Iris, Bichler, Edyta K., García, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572268/
https://www.ncbi.nlm.nih.gov/pubmed/28878632
http://dx.doi.org/10.3389/fnsys.2017.00058