Cargando…
Human Blood CD1c(+) Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4(+) T Cells
Dendritic cells (DC) initiate the differentiation of CD4(+) helper T cells into effector cells including Th1 and Th17 responses that play an important role in inflammation and autoimmune disease pathogenesis. In mice, Th1 and Th17 responses are regulated by different conventional (c) DC subsets, wit...
Autores principales: | Leal Rojas, Ingrid M., Mok, Wai-Hong, Pearson, Frances E., Minoda, Yoshihito, Kenna, Tony J., Barnard, Ross T., Radford, Kristen J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572390/ https://www.ncbi.nlm.nih.gov/pubmed/28878767 http://dx.doi.org/10.3389/fimmu.2017.00971 |
Ejemplares similares
-
Human CD141(+) Dendritic Cell and CD1c(+) Dendritic Cell Undergo Concordant Early Genetic Programming after Activation in Humanized Mice In Vivo
por: Minoda, Yoshihito, et al.
Publicado: (2017) -
Plasticity of Migrating CD1b(+) and CD1b(-) Lymph Dendritic Cells in the Promotion of Th1, Th2 and Th17 in Response to Salmonella and Helminth Secretions
por: Olivier, Michel, et al.
Publicado: (2013) -
Inhibition of CD4+CD25+ Regulatory T Cell Function and Conversion into Th1-Like Effectors by a Toll-Like Receptor-Activated Dendritic Cell Vaccine
por: Lee, Major K., et al.
Publicado: (2013) -
Human CD141(+) dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model
por: Lee, Yoke Seng, et al.
Publicado: (2021) -
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141(+) dendritic cells to activate naïve and memory WT1‐specific CD8(+) T cells
por: Pearson, Frances E, et al.
Publicado: (2020)