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Intracellular pH Regulates TRAIL-Induced Apoptosis and Necroptosis in Endothelial Cells

During ischemia or inflammation of organs, intracellular pH can decrease if acid production exceeds buffering capacity. Thus, the microenvironment can expose parenchymal cells to a reduced extracellular pH which can alter pH-dependent intracellular functions. We have previously shown that while sile...

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Detalles Bibliográficos
Autores principales: Zhang, Zhu-Xu, Gan, Ingrid, Pavlosky, Alexander, Huang, Xuyan, Fuhrmann, Benjamin, Jevnikar, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572609/
https://www.ncbi.nlm.nih.gov/pubmed/28884134
http://dx.doi.org/10.1155/2017/1503960