Deficient Insulin-mediated Upregulation of the Equilibrative Nucleoside Transporter 2 Contributes to Chronically Increased Adenosine in Diabetic Glomerulopathy

Deficient insulin signaling is a key event mediating diabetic glomerulopathy. Additionally, diabetic kidney disease has been related to increased levels of adenosine. Therefore, we tested a link between insulin deficiency and dysregulated activity of the equilibrative nucleoside transporters (ENTs)...

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Detalles Bibliográficos
Autores principales: Alarcón, Sebastián, Garrido, Wallys, Vega, Génesis, Cappelli, Claudio, Suárez, Raibel, Oyarzún, Carlos, Quezada, Claudia, San Martín, Rody
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572683/
https://www.ncbi.nlm.nih.gov/pubmed/28842605
http://dx.doi.org/10.1038/s41598-017-09783-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572683/
https://www.ncbi.nlm.nih.gov/pubmed/28842605
http://dx.doi.org/10.1038/s41598-017-09783-0

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