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Deficient Insulin-mediated Upregulation of the Equilibrative Nucleoside Transporter 2 Contributes to Chronically Increased Adenosine in Diabetic Glomerulopathy
Deficient insulin signaling is a key event mediating diabetic glomerulopathy. Additionally, diabetic kidney disease has been related to increased levels of adenosine. Therefore, we tested a link between insulin deficiency and dysregulated activity of the equilibrative nucleoside transporters (ENTs)...
Autores principales: | Alarcón, Sebastián, Garrido, Wallys, Vega, Génesis, Cappelli, Claudio, Suárez, Raibel, Oyarzún, Carlos, Quezada, Claudia, San Martín, Rody |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572683/ https://www.ncbi.nlm.nih.gov/pubmed/28842605 http://dx.doi.org/10.1038/s41598-017-09783-0 |
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